Dostinex (Cabergoline) 0.5mg/2tabs – Pfizer USA


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Dostinex 0.5 mg Cabergoline 2 Tablets

Cabergoline (brand name Dostinex by Pfizer and Cabaser) is a medicine which is a potent agonist at dopamine D2 receptors, which are derived from fruit body of the fungus species ergot (Claviceps purpurea). In vitro studies in rats have shown that cabergoline has a direct inhibitory effect on the production of prolactin in the pituitary gland. Dostinex can have serious side effects and use should only take place under the careful guidance of specialist and regular follow-ups.

Dostinex, also known as Cabergoline, is a medication primarily used to treat conditions associated with high levels of the hormone prolactin in the body.

Dostinex is highly regarded for its effectiveness in managing hyperprolactinemia, a condition characterized by an excess of prolactin production. It offers several potential benefits and is commonly prescribed by healthcare professionals.

Here are some key benefits and uses of Dostinex:

  • Treatment of Hyperprolactinemia: Dostinex is primarily used to lower prolactin levels in individuals with hyperprolactinemia. This condition can cause symptoms such as irregular menstrual periods, infertility, breast milk production in non-pregnant women, and decreased libido in both men and women. Dostinex helps restore normal prolactin levels and alleviate associated symptoms.
  • Management of Prolactinomas: Dostinex is also used to treat prolactin-secreting pituitary tumors known as prolactinomas. These tumors can lead to elevated prolactin levels and associated symptoms. Dostinex helps shrink these tumors and reduce prolactin secretion.
  • Improved Fertility: In individuals with hyperprolactinemia-related infertility, Dostinex can restore normal ovulation and increase the chances of pregnancy. By lowering prolactin levels, Dostinex improves reproductive function and hormonal balance.
  • Management of Parkinson’s Disease: Dostinex has shown potential benefits in the management of Parkinson’s disease. It acts on dopamine receptors and helps improve motor symptoms associated with this neurodegenerative disorder.

While Dostinex is generally well-tolerated, it may have potential side effects, including but not limited to nausea, dizziness, headache, and gastrointestinal disturbances.

Dosage and administration

Parkinson’s disease : A low starting dose ( 1 mg ) , very slow dose escalation due . the long plasma half-life ( beginning with 0.5-1 mg per week , later every other week ) . The usual maintenance dose in combination with levodopa : 2.6 mg once a day.

Prolactin lowering treatment

1 mg within 24 hours after birth . If it fails to effect , the dose may be repeated after 6-8 hours . Effect is usually obtained within 3 hours and lasts for several weeks. Treatment should be initiated under specialist supervision and must be evaluated periodically for clinical efficacy and risk of serious side effects.

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